Introduction: Asthma remains a major public health problem, with 300 million people affected worldwide and a low rate of adherence to treatment. Context: Few authors have considered one of the determinants of asthmatic patients’ adherence to treatment: the accompaniment offered by health care professionals. Aim: To describe the expectations and needs of people living with chronic asthma regarding their accompaniment. Methods: A descriptive qualitative approach with reasoned sampling. Eight individual semi-structured interviews were conducted among chronic asthmatic adult patients and analyzed by an inductive approach. This was submitted to participants for validation. Results: Needs and expectations are branched out into six main themes: the wish to establish a trusting relationship, the need to perceive professional competence, the importance of the professional’s availability, the wish to be more involved in one’s life with the disease, the desire for the professional to adopt a humanist posture and to take into account patient singularity. Conclusion: A better understanding of non-met expectations would help the adherence to treatment rate to improve. This qualitative research opens various avenues for reflection that are worth thinking about and provides the breeding ground for other studies.