Introduction/Background: the development of a cancerous disease sometimes results in the externalization of the tumor to the skin, creating a malignant wound. Limited data describe the coping strategies that individuals use to deal with this situation. Aim: the main objective is to determine the different adaptation strategies used by patients with malignant wounds, and links with their clinical and sociodemographic characteristics. The secondary objective is to document the body image of these individuals. Materials and methods: an analytical study was carried out on twenty-one patients with a malignant wound, hospitalized in medical oncology. The French versions of Vitaliano’s coping scale and the Body Image Scale were used. Results: patients with malignant wounds use three coping strategies: problem, emotional, and social support research. The pain of the wound is positively associated with emotional coping and the length of the cancer diagnosis with seeking social support. Body image seems to be impaired. Discussion/Conclusion: adjusting to the malignant wound seems possible with care support provisions such as pain relief and/or counseling. A national study is currently trying to generalize these results.