The so-called “sandwich generation” (SG) is characterized by concurrent and competing professional, familial, and informal caregiving workloads. These stressors pose potential health risks. However, the current knowledge about SG characteristics and perceived state of health are insufficient to allow occupational health nurses to develop evidence-based interventions designed for health promotion. We aimed to describe this population and examine the relationships between these coexisting workloads and their perceived health. This study is based on a descriptive, correlational design. Employees of a Swiss public authority completed an electronic questionnaire. Of 844 respondents, 23 % were SG members. Ages of elderly parents or parents-in-law, co-residence with the latter, and having children still living at home are indicators that employees could be members of the SG. Perceived physical health status of SG members was rated better than their mental health status. The heterogeneity of the SG was reflected in three clusters. Finally, physical health score was the only one that differed from the other health scores adjusting for clusters and sex. This study provides a foundation for developing preventive interventions targeting the SG.