Health professionals have to work together to ensure quality patient care. While many studies explore interprofessional education and practice, interprofessional knowledge is related to teamwork and organizational context. Some frameworks include “patient-centered” concepts to highlight the contribution of the patient, but descriptions of the patient’s contribution to interprofessional practice are limited. Nursing professionals develop extensive expertise as a patient-centered professional practice and their experience can inspire new collaborative approaches. This article aims to summarize the state of knowledge regarding interprofessional practice and patient-centered nursing expertise. We also highlight the contribution of nursing in developing this approach and the ways in which nursing contributes to the development of interprofessional knowledge that is consistent with its values.