A reflection on the evolution of the nursing discipline requires us to question various motives borrowed from other disciplines. While some may be reluctant to borrow, they also believe that borrowing undermines the assertion and autonomy of the discipline itself. This text suggests defining the nursing discipline based on the merits of the confluences, heritages, and plurality that make up its landscape. Advocating that the discipline is fundamentally heterogeneous, the author demonstrates that the creole metaphor can be relevant because of the identity and interdisciplinary pitfalls that it conveys, in addition to the quest for emancipation and recognition that underlies it. From there, he illustrates the processes of syncretism that are at play using an analysis of knowledge borrowed from humanities and social sciences. By tracking the content flows, he identifies the logic of “breaking” and reinterpreting, rendering them intelligible and relevant for the discipline of nursing. This text concludes with some requirements that would accompany the creole metaphor, supposing it were to be taken up within the discipline.